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Literature summary extracted from

  • Thomä, N.H.; Iakovenko, A.; Owen, D.; Scheidig, A.S.; Waldmann, H.; Goody, R.S.; Alexandrov, K.
    Phosphoisoprenoid binding specificity of geranylgeranyltransferase type II (2000), Biochemistry, 39, 12043-12052.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.60 expression in SF21 cells Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.5.1.60 Mg2+ not requirement Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.60 Rattus norvegicus
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.5.1.60 geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate mechanism Rattus norvegicus
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.60 geranylgeranyl diphosphate + protein-cysteine
-
 Rattus norvegicus S-geranylgeranyl-protein + diphosphate
-
 ?
2.5.1.60 additional information farnesyl diphosphate and geranylgeranyl diphosphate bind to enzyme with very similar rate constant, but the binding mechanism of farnesyl diphosphate differs from that of geranylgeranyl diphosphate, shortening of the isoprenoid chain leads to a drastic decreases in affinity Rattus norvegicus ?
-
 ?