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Literature summary extracted from

  • Gentzsch, M.; Tanner, W.
    The PMT gene family: protein O-glycosylation in Saccharomyces cerevisiae is vital (1996), EMBO J., 15, 5752-5759.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.109
-
 Saccharomyces cerevisiae

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.109 additional information construction of all single, double and triple mutants of the genes PMT1-4 by gene disruption and crosses, characterization concerning growth, morphology, and their sensitivity to killer toxin K1, sorbitol dependence, caffeine and calcofluor white, overview Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.109 dolichyl phosphate D-mannose + protein Saccharomyces cerevisiae acceptor substrates: secretory proteins dolichyl phosphate + O-D-mannosylprotein
-
 ?
2.4.1.109 dolichyl phosphate D-mannose + protein Saccharomyces cerevisiae production of cell-wall mannoproteins dolichyl phosphate + O-D-mannosylprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.109 Saccharomyces cerevisiae P31382 PMT2
-
2.4.1.109 Saccharomyces cerevisiae P33775 gene PMT1
-
2.4.1.109 Saccharomyces cerevisiae P42934 gene PMT6
-
2.4.1.109 Saccharomyces cerevisiae P46971 gene PMT4
-
2.4.1.109 Saccharomyces cerevisiae P47190 gene PMT3
-
2.4.1.109 Saccharomyces cerevisiae P52867 gene PMT5
-
2.4.1.109 Saccharomyces cerevisiae Q06644 gene PMT7
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.109 dolichyl phosphate D-mannose + protein the enzyme transfers mannosyl residues to the hydroxyl of serine or threonine residues Saccharomyces cerevisiae dolichyl phosphate + O-D-mannosylprotein
-
 ?
2.4.1.109 dolichyl phosphate D-mannose + protein acceptor substrates: secretory proteins Saccharomyces cerevisiae dolichyl phosphate + O-D-mannosylprotein
-
 ?
2.4.1.109 dolichyl phosphate D-mannose + protein production of cell-wall mannoproteins Saccharomyces cerevisiae dolichyl phosphate + O-D-mannosylprotein
-
 ?
2.4.1.109 dolichyl phosphate D-mannose + Tyr-Ala-Thr-Ala-Val wild-type and mutants Saccharomyces cerevisiae dolichyl phosphate + O-D-mannosyl-Tyr-Ala-Thr-Ala-Val
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.109 PMT
-
 Saccharomyces cerevisiae