Literature summary extracted from

Klier, H.; Csonga, R.; Steinkasserer, A.; Woehl, T.; Lottspeich, F.; Eder, J.
Purification and characterization of human deoxyhypusine synthase from HeLa cells (1995), FEBS Lett., 364, 207-210.

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
2.5.1.46	41000	-	4 * 41000, SDS-PAGE	Homo sapiens
2.5.1.46	150000	-	gel filtration	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.46	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.5.1.46	HeLa cell	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
2.5.1.46	0.00325	-	-	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.46	[eIF5A-precursor]-lysine + spermidine	-	Homo sapiens	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	i.e. [eIF5A-precursor]-N6-(4-aminobutyl)lysine	?

Subunits

EC Number	Subunits	Comment	Organism
2.5.1.46	tetramer	4 * 41000, SDS-PAGE	Homo sapiens

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
2.5.1.46	9	-	-	Homo sapiens

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.5.1.46	NAD+	-	Homo sapiens

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Release 2023.1 (January 2023)