EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.4.2.19 | - |
Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.19 | 5-phosphoribosyl-1-diphosphate | inhibition at alkaline pH and at physiological pH, pH 7.4, but not at an acidic pH, competitive for quinolinate. In presence of 30% glycerol, both the kidney and liver enzyme are inhibited, even at acidic pH | Sus scrofa |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.19 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.2.19 | kidney | - |
Sus scrofa | - |
2.4.2.19 | liver | - |
Sus scrofa | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.4.2.19 | 0.0227 | 0.0919 | enzyme from kidney | Sus scrofa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.19 | pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Sus scrofa | nicotinate D-ribonucleotide + diphosphate + CO2 | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.4.2.19 | 5.5 | - |
in presence of 1 mM 5-phospho-alpha-D-ribose 1-diphosphate, enzyme from kidney | Sus scrofa |
2.4.2.19 | 6 | - |
in presence of 1 mM 5-phospho-alpha-D-ribose 1-diphosphate, enzyme from liver | Sus scrofa |
2.4.2.19 | 9 | - |
in presence of 0.4 mM 5-phospho-alpha-D-ribose 1-diphosphate, enzyme from kidney and liver | Sus scrofa |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.19 | 0.05 | - |
5-phosphoribosyl-1-diphosphate | enzyme from liver | Sus scrofa | |
2.4.2.19 | 0.8 | - |
5-phosphoribosyl-1-diphosphate | enzyme from kidney | Sus scrofa |