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Literature summary extracted from

  • Reddy, C.C.; Li, N.Q.; Tu, C.P.D.
    Identification of a new glutathione S-transferase from rat liver cytosol (1984), Biochem. Biophys. Res. Commun., 121, 1014-1020.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.18 cytosol
-
 Rattus norvegicus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.5.1.18 24400
-
 2 * 24400, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.18 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.18 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.5.1.18 0.12
-
 with cumene hydroperoxide as substrate Rattus norvegicus
2.5.1.18 0.18
-
 with 4-nitrophenyl acetate as substrate Rattus norvegicus
2.5.1.18 0.34
-
 with ethacrynic acid as substrate Rattus norvegicus
2.5.1.18 0.4
-
 with 1,2-epoxy-3-(4-nitrophenoxy)propane as substrate Rattus norvegicus
2.5.1.18 1.8
-
 with 1-chloro-2,4-dinitrobenzene as substrate Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.18 glutathione + 1,2-dichloro-4-nitrobenzene
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + 1,2-epoxy-3-(4-nitrophenoxy)propane
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene
-
 Rattus norvegicus S-2,4-dinitrophenylglutathione + HCl
-
 ?
2.5.1.18 glutathione + 4-nitrobenzyl chloride
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + 4-nitrophenyl acetate
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + 4-nitropyridine
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + androst-5-ene-3,17-dione
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + bromosulfophthalein
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + cumene hydroperoxide
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + ethacrynic acid
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + linoleic acid hydroperoxide
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 glutathione + tert-butyl hydroperoxide
-
 Rattus norvegicus ?
-
 ?
2.5.1.18 additional information specificity Rattus norvegicus ?
-
 ?
2.5.1.18 RX + glutathione RX: R: aliphatic, aromatic or heterocyclic, X: sulfate, nitrite or halide, enzyme also catalyzes: the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrite, certain isomerization reactions and disulfide interchange Rattus norvegicus HX + R-S-glutathione
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.18 dimer 2 * 24400, SDS-PAGE Rattus norvegicus