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Literature summary extracted from

  • Slominska, E.M.; Kalsi, K.K.; Yacoub, M.H.; Smolenski, R.T.
    The role of 5'-deoxy-5'-methyl thioadenosine phosphorylase in cardiac adenosine breakdown and adenine production (2000), Adv. Exp. Med. Biol., 486, 159-162.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.28 0.014
-
 5'-deoxy-5'-methylthioadenosine
-
 Homo sapiens
2.4.2.28 0.184
-
 adenosine
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.28 5'-deoxy-5'-methylthioadenosine + phosphate Homo sapiens involved in cardiac purine breakdown during ischemia adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.28 Homo sapiens
-
-
-
2.4.2.28 Rattus norvegicus
-
 Wistar
-
2.4.2.28 Rattus norvegicus Wistar
-
 Wistar
-
2.4.2.28 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.28 heart left ventricular specimen Homo sapiens
-
2.4.2.28 heart left ventricular specimen Rattus norvegicus
-
2.4.2.28 heart left ventricular specimen Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.2.28 additional information
-
-
 Homo sapiens
2.4.2.28 additional information
-
-
 Rattus norvegicus
2.4.2.28 additional information
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.28 5'-deoxy-5'-methylthioadenosine + phosphate
-
 Homo sapiens adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
2.4.2.28 5'-deoxy-5'-methylthioadenosine + phosphate
-
 Rattus norvegicus adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
2.4.2.28 5'-deoxy-5'-methylthioadenosine + phosphate
-
 Sus scrofa adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
2.4.2.28 5'-deoxy-5'-methylthioadenosine + phosphate involved in cardiac purine breakdown during ischemia Homo sapiens adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
2.4.2.28 5'-deoxy-5'-methylthioadenosine + phosphate
-
 Rattus norvegicus Wistar adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
2.4.2.28 adenosine + phosphate
-
 Homo sapiens adenine + D-ribose 1-phosphate
-
 ?
2.4.2.28 adenosine + phosphate
-
 Rattus norvegicus adenine + D-ribose 1-phosphate
-
 ?
2.4.2.28 adenosine + phosphate
-
 Sus scrofa adenine + D-ribose 1-phosphate
-
 ?
2.4.2.28 adenosine + phosphate
-
 Rattus norvegicus Wistar adenine + D-ribose 1-phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.2.28 37
-
 assay at Homo sapiens
2.4.2.28 37
-
 assay at Rattus norvegicus
2.4.2.28 37
-
 assay at Sus scrofa