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Literature summary extracted from

  • Buckner, F.S.; Yokoyama, K.; Nguyen, L.; Grewal, A.; Erdjument-Bromage, H.; Tempst, P.; Strickland, C.L.; Xiao, L.; Van Voorhis, W.C.; Gelb, M.H.
    Cloning, heterologous expression, and distinct substrate specificity of protein farnesyltransferase from Trypanosoma brucei (2000), J. Biol. Chem., 275, 21870-21876.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.58 expression in bloodstream and insect stage parasites, and expression in Escherichia coli Trypanosoma brucei brucei

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.58 Trypanosoma brucei brucei
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-
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Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.58
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 Trypanosoma brucei brucei

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.58 bloodstream form
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 Trypanosoma brucei brucei
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2.5.1.58 procyclic form
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 Trypanosoma brucei brucei
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.58 farnesyl diphosphate + protein-cysteine enzyme prefers Gln and Met at the X position but not Ser, Thr or Cys, which are good substrates for mammalian enzyme Trypanosoma brucei brucei diphosphate + S-farnesyl protein
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 ?