Literature summary extracted from

Marcotte,P.; Walsh, C.
Active site-directed inactivation of cystathionine gamma-synthetase and glutamic pyruvic transaminase by propargylglycine (1975), Biochem. Biophys. Res. Commun., 62, 677-682.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.5.1.48	propargylglycine	i.e. 2-amino-4-pentynoate	Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.48	Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.48	O-succinyl-L-homoserine + H2O	-	Salmonella enterica subsp. enterica serovar Typhimurium	succinate + 2-oxobutyrate + NH3	-	?
2.5.1.48	O-succinyl-L-homoserine + L-cysteine	-	Salmonella enterica subsp. enterica serovar Typhimurium	L-cystathionine + succinate	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.5.1.48	pyridoxal 5'-phosphate	-	Salmonella enterica subsp. enterica serovar Typhimurium

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Release 2023.1 (January 2023)