Literature summary extracted from

Posner B.I.
Cystathionine-synthase: studies on the replacement reaction (1972), Biochim. Biophys. Acta, 276, 277-283.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.5.1.48	beta-mercaptopropionate	also a substrate for gamma-replacement reaction	Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.5.1.48	additional information	-	additional information	kinetic analysis of the reaction O-succinyl-L-homoserine + beta-mercaptopropionate	Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.48	Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.48	O-succinyl-L-homoserine + beta-mercaptopropionate	-	Salmonella enterica subsp. enterica serovar Typhimurium	S-carboxyethyl-L-homocysteine + succinate	-	?
2.5.1.48	O-succinyl-L-homoserine + H2O	-	Salmonella enterica subsp. enterica serovar Typhimurium	succinate + 2-oxobutyrate + NH3	-	?
2.5.1.48	O-succinyl-L-homoserine + L-cysteine	-	Salmonella enterica subsp. enterica serovar Typhimurium	L-cystathionine + succinate	-	?

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Release 2023.1 (January 2023)