Literature summary extracted from

Daum, S.; Tai, C.H.; Cook, P.F.
Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction (2003), Biochemistry, 42, 106-113.

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.5.1.47	S272A	mutant enzyme catalyzes the overall reaction, first half-reaction is decreased by factor 3, the decrease in rate of elimination is compensated by an increase in affinity for O-acetyl-L-Ser	Salmonella enterica subsp. enterica serovar Typhimurium
2.5.1.47	S272D	mutant enzyme catalyzes the overall reaction	Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.47	Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.47	O-acetyl-L-Ser + H2S	-	Salmonella enterica subsp. enterica serovar Typhimurium	L-Cys + acetate	-	?

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Release 2023.1 (January 2023)