Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Yoshimura, T.; Tanizawa, K.; Tanaka, H.; Soda, K.
    The effect of carboxylates and halides on L-lysine 6-aminotransferase-catalyzed reactions (1984), J. Biochem., 95, 559-565.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.6.1.36 acetate stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 Br- stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 Cl- stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 F- stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 formate stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 I- stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.36 acetate stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 Br- stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 Cl- stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 F- stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 formate stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 I- stimulates alanine transamination, inhibits lysine transamination [Flavobacterium] lutescens
2.6.1.36 Phenylglyoxal loss of activity with lysine, no effect on activity with L-alanine [Flavobacterium] lutescens
2.6.1.36 propionate inhibits alanine transamination and lysine transamination [Flavobacterium] lutescens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.36 L-lysine + 2-oxoglutarate [Flavobacterium] lutescens
-
 2-aminoadipate 6-semialdehyde + L-glutamate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.36 [Flavobacterium] lutescens
-
 IFO 3084
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.36 L-alanine + 2-oxoglutarate very slow [Flavobacterium] lutescens pyruvate + L-glutamate
-
 ?
2.6.1.36 L-lysine + 2-oxoglutarate
-
 [Flavobacterium] lutescens 2-aminoadipate 6-semialdehyde + L-glutamate
-
 ?