BRENDA - Enzyme Database

Activation of mannosyltransferase II by nonbilayer phospholipids

Jensen, J.W.; Schutzbach, J.S.; Biochemistry 23, 1115-1119 (1984)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.4.1.132
phosphatidylethanolamine
activation
Oryctolagus cuniculus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.1.132
Phospholipids
stable bilayer forming, e.g. phosphatidylcholine, restorable by addition of cholesterol, dolichol and dolichol-derivatives
Oryctolagus cuniculus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.1.132
microsome
-
Oryctolagus cuniculus
-
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
Oryctolagus cuniculus
involved in the biosynthesis of asparagine-linked saccharide chains of mammalian glycoproteins
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
-
-
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
Oryctolagus cuniculus
the 1,3-linked mannosyl residue in mammalian lipid-linked oligosaccharide of the structure Glc3Man9GlcNAc2 is produced by this enzyme
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.4.1.132
Oryctolagus cuniculus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.1.132
liver
-
Oryctolagus cuniculus
-
Storage Stability
EC Number
Storage Stability
Organism
2.4.1.132
glycerol, 10% v/v, stabilizes during storage
Oryctolagus cuniculus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
-
636753
Oryctolagus cuniculus
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
636753
Oryctolagus cuniculus
?
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
involved in the biosynthesis of asparagine-linked saccharide chains of mammalian glycoproteins
636753
Oryctolagus cuniculus
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
-
-
-
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
the 1,3-linked mannosyl residue in mammalian lipid-linked oligosaccharide of the structure Glc3Man9GlcNAc2 is produced by this enzyme
636753
Oryctolagus cuniculus
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
-
-
-
Temperature Optimum [C]
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
2.4.1.132
37
-
assay at
Oryctolagus cuniculus
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.4.1.132
phosphatidylethanolamine
activation
Oryctolagus cuniculus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.1.132
Phospholipids
stable bilayer forming, e.g. phosphatidylcholine, restorable by addition of cholesterol, dolichol and dolichol-derivatives
Oryctolagus cuniculus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.1.132
microsome
-
Oryctolagus cuniculus
-
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
Oryctolagus cuniculus
involved in the biosynthesis of asparagine-linked saccharide chains of mammalian glycoproteins
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
-
-
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
Oryctolagus cuniculus
the 1,3-linked mannosyl residue in mammalian lipid-linked oligosaccharide of the structure Glc3Man9GlcNAc2 is produced by this enzyme
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.1.132
liver
-
Oryctolagus cuniculus
-
Storage Stability (protein specific)
EC Number
Storage Stability
Organism
2.4.1.132
glycerol, 10% v/v, stabilizes during storage
Oryctolagus cuniculus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
-
636753
Oryctolagus cuniculus
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
636753
Oryctolagus cuniculus
?
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
involved in the biosynthesis of asparagine-linked saccharide chains of mammalian glycoproteins
636753
Oryctolagus cuniculus
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
-
-
-
2.4.1.132
GDPmannose + tetrasaccharide-diphosphoryl-lipid
the 1,3-linked mannosyl residue in mammalian lipid-linked oligosaccharide of the structure Glc3Man9GlcNAc2 is produced by this enzyme
636753
Oryctolagus cuniculus
GDP + mannosyl-alpha-1,3-tetrasaccharide-diphosphoryl-lipid
-
-
-
-
Temperature Optimum [C] (protein specific)
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
2.4.1.132
37
-
assay at
Oryctolagus cuniculus