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Literature summary extracted from

  • Nagayama, H.; Muramatsu, M.; Shimura, K.
    Enzymatic formation of aminomalonic acid from ketomalonic acid (1958), Nature, 181, 417-418.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.47 benzoquinone 1 mM, 84% inhibition Bombyx mori
2.6.1.47 hydroxylamine 2 mM, 58% inhibition Bombyx mori
2.6.1.47 KCN 1 mM, 38% inhibition Bombyx mori
2.6.1.47 p-chloromercuribenzoate 1 mM, 99% inhibition Bombyx mori

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.47 DL-alanine + oxomalonate Rattus norvegicus glutamate, 2-aminobutyrate, aspartate can also act as amino donors in decreasing order of reactivity, probably involved in the biosynthesis of glycine pyruvate + aminomalonic acid
-
 ?
2.6.1.47 DL-alanine + oxomalonate Bombyx mori glutamate, 2-aminobutyrate, aspartate can also act as amino donors in decreasing order of reactivity, probably involved in the biosynthesis of glycine pyruvate + aminomalonic acid
-
 ?
2.6.1.47 DL-alanine + oxomalonate Oryctolagus cuniculus glutamate, 2-aminobutyrate, aspartate can also act as amino donors in decreasing order of reactivity, probably involved in the biosynthesis of glycine pyruvate + aminomalonic acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.47 Bombyx mori
-
-
-
2.6.1.47 Oryctolagus cuniculus
-
-
-
2.6.1.47 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.47 partial Bombyx mori

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.47 heart
-
 Oryctolagus cuniculus
-
2.6.1.47 liver
-
 Rattus norvegicus
-
2.6.1.47 liver
-
 Oryctolagus cuniculus
-
2.6.1.47 silk gland posterior Bombyx mori
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.47 DL-alanine + oxomalonate glutamate, 2-aminobutyrate and aspartate can also act as amino donors in decreasing order of reactivity Rattus norvegicus pyruvate + aminomalonic acid
-
 ?
2.6.1.47 DL-alanine + oxomalonate glutamate, 2-aminobutyrate and aspartate can also act as amino donors in decreasing order of reactivity Bombyx mori pyruvate + aminomalonic acid
-
 ?
2.6.1.47 DL-alanine + oxomalonate glutamate, 2-aminobutyrate and aspartate can also act as amino donors in decreasing order of reactivity Oryctolagus cuniculus pyruvate + aminomalonic acid
-
 ?
2.6.1.47 DL-alanine + oxomalonate glutamate, 2-aminobutyrate, aspartate can also act as amino donors in decreasing order of reactivity, probably involved in the biosynthesis of glycine Rattus norvegicus pyruvate + aminomalonic acid
-
 ?
2.6.1.47 DL-alanine + oxomalonate glutamate, 2-aminobutyrate, aspartate can also act as amino donors in decreasing order of reactivity, probably involved in the biosynthesis of glycine Bombyx mori pyruvate + aminomalonic acid
-
 ?
2.6.1.47 DL-alanine + oxomalonate glutamate, 2-aminobutyrate, aspartate can also act as amino donors in decreasing order of reactivity, probably involved in the biosynthesis of glycine Oryctolagus cuniculus pyruvate + aminomalonic acid
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.47 37
-
 assay at Bombyx mori

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.47 9 9.2
-
 Bombyx mori