BRENDA - Enzyme Database

alpha-Aminoadipate and kynurenine aminotransferase activities from rat kidney. Evidence for separate identity

Mawal, M.R.; Deshmukh, D.R.; J. Biol. Chem. 266, 2573-2575 (1991)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.6.1.7
additional information
not inhibited by antibodies against 2-aminoadipate transaminase
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.6.1.39
mitochondrion
-
Rattus norvegicus
5739
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.6.1.7
Rattus norvegicus
-
-
-
2.6.1.39
Rattus norvegicus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
2.6.1.7
-
Rattus norvegicus
2.6.1.39
-
Rattus norvegicus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.6.1.7
kidney
-
Rattus norvegicus
-
2.6.1.39
kidney
-
Rattus norvegicus
-
2.6.1.39
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
2.6.1.7
3.5
-
-
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.6.1.7
L-kynurenine + 2-oxoglutarate
-
636622
Rattus norvegicus
kynurenic acid + L-glutamate + H2O
-
636622
Rattus norvegicus
-
2.6.1.39
additional information
KAT and AadAT activities are associated with 2 different proteins
636622
Rattus norvegicus
?
-
-
-
-
Temperature Optimum [░C]
EC Number
Temperature Optimum [░C]
Temperature Optimum Maximum [░C]
Commentary
Organism
2.6.1.7
37
-
assay at
Rattus norvegicus
pH Stability
EC Number
pH Stability
pH Stability Maximum
Commentary
Organism
2.6.1.7
4.5
-
75 min, inactivation, t1/2: 30 min
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.6.1.7
additional information
not inhibited by antibodies against 2-aminoadipate transaminase
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.6.1.39
mitochondrion
-
Rattus norvegicus
5739
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
2.6.1.7
-
Rattus norvegicus
2.6.1.39
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.6.1.7
kidney
-
Rattus norvegicus
-
2.6.1.39
kidney
-
Rattus norvegicus
-
2.6.1.39
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
2.6.1.7
3.5
-
-
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.6.1.7
L-kynurenine + 2-oxoglutarate
-
636622
Rattus norvegicus
kynurenic acid + L-glutamate + H2O
-
636622
Rattus norvegicus
-
2.6.1.39
additional information
KAT and AadAT activities are associated with 2 different proteins
636622
Rattus norvegicus
?
-
-
-
-
Temperature Optimum [░C] (protein specific)
EC Number
Temperature Optimum [░C]
Temperature Optimum Maximum [░C]
Commentary
Organism
2.6.1.7
37
-
assay at
Rattus norvegicus
pH Stability (protein specific)
EC Number
pH Stability
pH Stability Maximum
Commentary
Organism
2.6.1.7
4.5
-
75 min, inactivation, t1/2: 30 min
Rattus norvegicus