EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.6.1.7 | adipate | - |
Rattus norvegicus | |
2.6.1.7 | azelaic acid | - |
Rattus norvegicus | |
2.6.1.7 | Decanoic acid | - |
Rattus norvegicus | |
2.6.1.7 | Diethylglutaric acid | - |
Rattus norvegicus | |
2.6.1.7 | dimethylglutaric acid | - |
Rattus norvegicus | |
2.6.1.7 | additional information | not inhibited by 2-aminoadipate; not inhibited by oxaloacetic acid, 3-methylglutaric acid | Rattus norvegicus | |
2.6.1.7 | pimelate | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.7 | 0.02 | - |
2-oxoglutarate | cosubstrate L-kynurenine | Rattus norvegicus | |
2.6.1.7 | 4 | - |
L-kynurenine | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.6.1.7 | soluble | - |
Rattus norvegicus | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.6.1.7 | additional information | - |
amino acid composition | Rattus norvegicus |
2.6.1.7 | 44000 | - |
2 * 44000, SDS-PAGE | Rattus norvegicus |
2.6.1.7 | 91000 | - |
gel filtration | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.39 | L-2-aminoadipate + 2-oxoglutarate | Rattus norvegicus | lysine catabolic pathway | 2-oxoadipate + L-glutamate | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.6.1.7 | Rattus norvegicus | - |
- |
- |
2.6.1.39 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.6.1.7 | - |
Rattus norvegicus |
2.6.1.39 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.6.1.7 | kidney | - |
Rattus norvegicus | - |
2.6.1.39 | kidney | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.6.1.7 | 4.22 | - |
- |
Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.7 | L-3-hydroxykynurenine + 2-oxoglutarate | - |
Rattus norvegicus | xanthurenic acid + L-glutamate | - |
? | |
2.6.1.7 | L-histidine + 2-oxoglutarate | - |
Rattus norvegicus | 3-(1H-imidazol-4-yl)-2-oxopropanoate + L-glutamate | - |
? | |
2.6.1.7 | L-kynurenine + 2-oxoglutarate | best substrates | Rattus norvegicus | kynurenic acid + L-glutamate + H2O | - |
? | |
2.6.1.7 | L-kynurenine + pyruvate | less effective than 2-oxoglutarate | Rattus norvegicus | kynurenic acid + L-alanine + H2O | - |
? | |
2.6.1.7 | L-tryptophan + 2-oxoglutarate | poor substrate | Rattus norvegicus | 3-indole-2-oxopropanoate + L-glutamate | - |
? | |
2.6.1.7 | L-tyrosine + 2-oxoglutarate | - |
Rattus norvegicus | 3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate | - |
? | |
2.6.1.39 | L-2-aminoadipate + 2-oxoglutarate | - |
Rattus norvegicus | 2-oxoadipate + L-glutamate | - |
r | |
2.6.1.39 | L-2-aminoadipate + 2-oxoglutarate | lysine catabolic pathway | Rattus norvegicus | 2-oxoadipate + L-glutamate | - |
r | |
2.6.1.39 | additional information | KAT and AadAT activities are associated with 2 different proteins | Rattus norvegicus | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.6.1.7 | dimer | 2 * 44000, SDS-PAGE | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.6.1.7 | More | not identical with EC 2.6.1.39 | Rattus norvegicus |
2.6.1.39 | AadAT | - |
Rattus norvegicus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.6.1.7 | 37 | - |
assay at | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.7 | additional information | - |
pI: 5.9 | Rattus norvegicus |