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Literature summary extracted from

  • Mason, M.
    Effects of calcium ions and quinolinic acid on rat kidney mitochondrial kynurenine aminotransferase (1974), Biochem. Biophys. Res. Commun., 60, 64-69.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.7 EGTA strong inhibition at pH 6.8 and Ca2+ concentrations below 0.5 mM Rattus norvegicus
2.6.1.7 additional information not inhibited by EGTA; not inhibited by quinolinate Rattus norvegicus
2.6.1.7 quinolinic acid strong inhibition at pH 6.8 and Ca2+ concentrations below 0.5 mM Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.6.1.7 mitochondrion
-
 Rattus norvegicus 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.6.1.7 CaCl2 approx. 4fold increase in activity at pH 6.4 Rattus norvegicus
2.6.1.7 additional information not activated by chloride salts of Mg2+, Mn2+, Na+, K+ or NH4+ Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.7 Rattus norvegicus
-
 Sprague-Dawley
-
2.6.1.7 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.7 L-kynurenine + 2-oxoglutarate
-
 Rattus norvegicus kynurenic acid + L-glutamate + H2O
-
 ?
2.6.1.7 L-kynurenine + 2-oxoglutarate
-
 Rattus norvegicus Sprague-Dawley kynurenic acid + L-glutamate + H2O
-
 ?