BRENDA - Enzyme Database

Subcellular distribution and properties of kynurenine transaminase in rat liver

Nakatani, M.; Morimoto, M.; Noguchi, T.; Kido, R.; Biochem. J. 143, 303-310 (1974)

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.6.1.7
1.6
-
L-kynurenine
pH 6.5, 37C, enzyme from supernatant
Rattus norvegicus
2.6.1.7
2.5
-
L-kynurenine
pH 6.5, 37C, mitochondrial enzyme
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.6.1.7
lysosome
10% of liver total activity at pH 6.5
Rattus norvegicus
5764
-
2.6.1.7
mitochondrion
-
Rattus norvegicus
5739
-
2.6.1.7
additional information
subcellular distribution
Rattus norvegicus
-
-
2.6.1.7
soluble
12% of liver total activity at pH 6.5
Rattus norvegicus
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.6.1.7
Rattus norvegicus
-
Donryu
-
2.6.1.7
Rattus norvegicus Donryu
-
Donryu
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.6.1.7
L-3-hydroxykynurenine + 2-oxoglutarate
-
636611
Rattus norvegicus
xanthurenic acid + L-glutamate
-
636611
Rattus norvegicus
-
2.6.1.7
L-3-hydroxykynurenine + 2-oxoglutarate
-
636611
Rattus norvegicus Donryu
xanthurenic acid + L-glutamate
-
636611
Rattus norvegicus Donryu
-
2.6.1.7
L-kynurenine + 2-oxoglutarate
-
636611
Rattus norvegicus
kynurenic acid + L-glutamate + H2O
-
636611
Rattus norvegicus
-
2.6.1.7
L-kynurenine + 2-oxoglutarate
-
636611
Rattus norvegicus Donryu
kynurenic acid + L-glutamate + H2O
-
636611
Rattus norvegicus Donryu
-
2.6.1.7
L-kynurenine + pyruvate
-
636611
Rattus norvegicus
kynurenic acid + L-alanine + H2O
-
636611
Rattus norvegicus
?
2.6.1.7
L-kynurenine + pyruvate
-
636611
Rattus norvegicus Donryu
kynurenic acid + L-alanine + H2O
-
636611
Rattus norvegicus Donryu
?
Temperature Optimum [C]
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
2.6.1.7
37
-
assay at
Rattus norvegicus
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.6.1.7
6
6.5
-
Rattus norvegicus
pH Range
EC Number
pH Minimum
pH Maximum
Commentary
Organism
2.6.1.7
6.5
8.8
maximal activity at pH 6.5, approx. half-maximal activity at pH 8.8
Rattus norvegicus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.6.1.7
1.6
-
L-kynurenine
pH 6.5, 37C, enzyme from supernatant
Rattus norvegicus
2.6.1.7
2.5
-
L-kynurenine
pH 6.5, 37C, mitochondrial enzyme
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.6.1.7
lysosome
10% of liver total activity at pH 6.5
Rattus norvegicus
5764
-
2.6.1.7
mitochondrion
-
Rattus norvegicus
5739
-
2.6.1.7
additional information
subcellular distribution
Rattus norvegicus
-
-
2.6.1.7
soluble
12% of liver total activity at pH 6.5
Rattus norvegicus
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.6.1.7
L-3-hydroxykynurenine + 2-oxoglutarate
-
636611
Rattus norvegicus
xanthurenic acid + L-glutamate
-
636611
Rattus norvegicus
-
2.6.1.7
L-3-hydroxykynurenine + 2-oxoglutarate
-
636611
Rattus norvegicus Donryu
xanthurenic acid + L-glutamate
-
636611
Rattus norvegicus Donryu
-
2.6.1.7
L-kynurenine + 2-oxoglutarate
-
636611
Rattus norvegicus
kynurenic acid + L-glutamate + H2O
-
636611
Rattus norvegicus
-
2.6.1.7
L-kynurenine + 2-oxoglutarate
-
636611
Rattus norvegicus Donryu
kynurenic acid + L-glutamate + H2O
-
636611
Rattus norvegicus Donryu
-
2.6.1.7
L-kynurenine + pyruvate
-
636611
Rattus norvegicus
kynurenic acid + L-alanine + H2O
-
636611
Rattus norvegicus
?
2.6.1.7
L-kynurenine + pyruvate
-
636611
Rattus norvegicus Donryu
kynurenic acid + L-alanine + H2O
-
636611
Rattus norvegicus Donryu
?
Temperature Optimum [C] (protein specific)
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
2.6.1.7
37
-
assay at
Rattus norvegicus
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.6.1.7
6
6.5
-
Rattus norvegicus
pH Range (protein specific)
EC Number
pH Minimum
pH Maximum
Commentary
Organism
2.6.1.7
6.5
8.8
maximal activity at pH 6.5, approx. half-maximal activity at pH 8.8
Rattus norvegicus