EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | 2,6-dichlorophenolindophenol | - |
Sus scrofa | |
1.6.3.1 | ATP | 2fold activation | Sus scrofa | |
1.6.3.1 | cytochrome c | - |
Sus scrofa | |
1.6.3.1 | menadione | - |
Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | Cd2+ | - |
Sus scrofa | |
1.6.3.1 | Mn2+ | - |
Sus scrofa | |
1.6.3.1 | additional information | inhibition by addition of hexokinase and glucose to remove ATP | Sus scrofa | |
1.6.3.1 | p-chloromercuribenzoate | - |
Sus scrofa | |
1.6.3.1 | sodium deoxycholate | no activity at 5 mg/ml | Sus scrofa | |
1.6.3.1 | Triton X-100 | no activity at 2 mg/ml | Sus scrofa | |
1.6.3.1 | Zn2+ | - |
Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.6.3.1 | 0.023 | - |
NADPH | pH 7, 37°C, 1.1 mM Ca2+ | Sus scrofa |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.6.3.1 | apical plasma membrane | - |
Sus scrofa | 16324 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | Ba2+ | very low activity | Sus scrofa | |
1.6.3.1 | Ca2+ | required for full activity | Sus scrofa | |
1.6.3.1 | Ca2+ | regulates enzyme activity | Sus scrofa | |
1.6.3.1 | Ca2+ | half maximal activity with 0.0001 mM Ca2+ | Sus scrofa | |
1.6.3.1 | Cd2+ | inhibitory | Sus scrofa | |
1.6.3.1 | additional information | Mg2+ has no effect | Sus scrofa | |
1.6.3.1 | Sr2+ | can replace for Ca2+ | Sus scrofa | |
1.6.3.1 | Zn2+ | inhibitory | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.3.1 | NAD(P)H + H+ + O2 | Sus scrofa | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | NAD(P)+ + H2O2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.3.1 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.6.3.1 | partial | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.6.3.1 | thyroid gland | - |
Sus scrofa | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.6.3.1 | 0.0007 | - |
pH 7., 37°C, 1.1 mM Ca2+ | Sus scrofa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.3.1 | NAD(P)H + H+ + O2 | - |
Sus scrofa | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | Sus scrofa | NAD(P)+ + H2O2 | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.6.3.1 | 0.0002 | - |
p-chloromercuribenzoate | - |
Sus scrofa |