BRENDA - Enzyme Database

Mechanism of C-3 hydrogen exchange and the elimination of ammonia in the 3-methylaspartate ammonia-lyase reaction

Botting, N.P.; Gani, D.; Biochemistry 31, 1509-1520 (1992)

Data extracted from this reference:

Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
4.3.1.2
K+
activates
Clostridium tetanomorphum
4.3.1.2
Mg2+
activates
Clostridium tetanomorphum
4.3.1.2
additional information
-
Clostridium tetanomorphum
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.3.1.2
L-threo-3-methylaspartate
Clostridium tetanomorphum
-
?
-
-
-
4.3.1.2
L-threo-3-methylaspartate
Clostridium tetanomorphum H1 / ATCC 15920
-
?
-
-
-
4.3.1.2
additional information
Clostridium tetanomorphum
enzyme is involved in the catabolic pathway for glutamate
?
-
-
-
4.3.1.2
additional information
Clostridium tetanomorphum H1 / ATCC 15920
enzyme is involved in the catabolic pathway for glutamate
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.3.1.2
Clostridium tetanomorphum
-
; ATCC 15920
-
4.3.1.2
Clostridium tetanomorphum H1 / ATCC 15920
-
-
-
Reaction
EC Number
Reaction
Commentary
Organism
4.3.1.2
L-threo-3-methylaspartate = mesaconate + NH3
carbon mechanism; kinetic mechanism
Clostridium tetanomorphum
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.3.1.2
L-aspartate
(2S)-aspartate
6058
Clostridium tetanomorphum
fumarate + NH3
-
-
-
-
4.3.1.2
L-aspartate
(2S)-aspartate
6058
Clostridium tetanomorphum H1 / ATCC 15920
fumarate + NH3
-
-
-
-
4.3.1.2
L-threo-3-methylaspartate
r
6058
Clostridium tetanomorphum
mesaconate + NH3
-
6058
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6058
Clostridium tetanomorphum
mesaconate + NH3
-
6058
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
r
6058
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6058
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6058
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6058
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
-
6058
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
L-threo-3-methylaspartate
-
6058
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
4.3.1.2
additional information
enzyme is involved in the catabolic pathway for glutamate
6058
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
additional information
enzyme is involved in the catabolic pathway for glutamate
6058
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
pH Range
EC Number
pH Minimum
pH Maximum
Commentary
Organism
4.3.1.2
additional information
-
-
Clostridium tetanomorphum
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
4.3.1.2
K+
activates
Clostridium tetanomorphum
4.3.1.2
Mg2+
activates
Clostridium tetanomorphum
4.3.1.2
additional information
-
Clostridium tetanomorphum
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.3.1.2
L-threo-3-methylaspartate
Clostridium tetanomorphum
-
?
-
-
-
4.3.1.2
L-threo-3-methylaspartate
Clostridium tetanomorphum H1 / ATCC 15920
-
?
-
-
-
4.3.1.2
additional information
Clostridium tetanomorphum
enzyme is involved in the catabolic pathway for glutamate
?
-
-
-
4.3.1.2
additional information
Clostridium tetanomorphum H1 / ATCC 15920
enzyme is involved in the catabolic pathway for glutamate
?
-
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.3.1.2
L-aspartate
(2S)-aspartate
6058
Clostridium tetanomorphum
fumarate + NH3
-
-
-
-
4.3.1.2
L-aspartate
(2S)-aspartate
6058
Clostridium tetanomorphum H1 / ATCC 15920
fumarate + NH3
-
-
-
-
4.3.1.2
L-threo-3-methylaspartate
r
6058
Clostridium tetanomorphum
mesaconate + NH3
-
6058
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6058
Clostridium tetanomorphum
mesaconate + NH3
-
6058
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
r
6058
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6058
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6058
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6058
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
-
6058
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
L-threo-3-methylaspartate
-
6058
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
4.3.1.2
additional information
enzyme is involved in the catabolic pathway for glutamate
6058
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
additional information
enzyme is involved in the catabolic pathway for glutamate
6058
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
pH Range (protein specific)
EC Number
pH Minimum
pH Maximum
Commentary
Organism
4.3.1.2
additional information
-
-
Clostridium tetanomorphum