BRENDA - Enzyme Database

Primary deuterium isotope effects for the 3-methylaspartase-catalyzed deamination of (2S)-aspartic acid, (2S,3S)-3-methylaspartic acid, and (2S,3S)-3-ethylaspartic acid

Botting, N.P.; Cohen, M.A.; Akhtar, M.; Gani, D.; Biochemistry 27, 2956-2959 (1988)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.3.1.2
L-threo-3-methylaspartate
Clostridium tetanomorphum
-
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.3.1.2
Clostridium tetanomorphum
-
; ATCC 15920
-
4.3.1.2
Clostridium tetanomorphum H1 / ATCC 15920
-
-
-
Reaction
EC Number
Reaction
Commentary
Organism
4.3.1.2
L-threo-3-methylaspartate = mesaconate + NH3
mechanism
Clostridium tetanomorphum
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.3.1.2
(2S,3R)-3-ethylaspartic acid
-
6056
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
(2S,3R)-3-ethylaspartic acid
-
6056
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
4.3.1.2
(2S,3S)-3-ethylaspartic acid
-
6056
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
L-aspartate
(2S,3R) [3-3H]aspartic acid
6056
Clostridium tetanomorphum
fumarate + NH3
amination 1.8 times faster than the amination of mesaconate
6056
Clostridium tetanomorphum
-
4.3.1.2
L-aspartate
(2S)-aspartate
6056
Clostridium tetanomorphum
fumarate + NH3
amination 1.8 times faster than the amination of mesaconate
6056
Clostridium tetanomorphum
-
4.3.1.2
L-aspartate
(2S,3R) [3-3H]aspartic acid
6056
Clostridium tetanomorphum H1 / ATCC 15920
fumarate + NH3
amination 1.8 times faster than the amination of mesaconate
6056
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-aspartate
(2S)-aspartate
6056
Clostridium tetanomorphum H1 / ATCC 15920
fumarate + NH3
amination 1.8 times faster than the amination of mesaconate
6056
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
r
6056
Clostridium tetanomorphum
mesaconate + NH3
-
6056
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6056
Clostridium tetanomorphum
mesaconate + NH3
-
6056
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
r
6056
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6056
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6056
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6056
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
-
6056
Clostridium tetanomorphum
?
-
-
-
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.3.1.2
L-threo-3-methylaspartate
Clostridium tetanomorphum
-
?
-
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.3.1.2
(2S,3R)-3-ethylaspartic acid
-
6056
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
(2S,3R)-3-ethylaspartic acid
-
6056
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
4.3.1.2
(2S,3S)-3-ethylaspartic acid
-
6056
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
L-aspartate
(2S,3R) [3-3H]aspartic acid
6056
Clostridium tetanomorphum
fumarate + NH3
amination 1.8 times faster than the amination of mesaconate
6056
Clostridium tetanomorphum
-
4.3.1.2
L-aspartate
(2S)-aspartate
6056
Clostridium tetanomorphum
fumarate + NH3
amination 1.8 times faster than the amination of mesaconate
6056
Clostridium tetanomorphum
-
4.3.1.2
L-aspartate
(2S,3R) [3-3H]aspartic acid
6056
Clostridium tetanomorphum H1 / ATCC 15920
fumarate + NH3
amination 1.8 times faster than the amination of mesaconate
6056
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-aspartate
(2S)-aspartate
6056
Clostridium tetanomorphum H1 / ATCC 15920
fumarate + NH3
amination 1.8 times faster than the amination of mesaconate
6056
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
r
6056
Clostridium tetanomorphum
mesaconate + NH3
-
6056
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6056
Clostridium tetanomorphum
mesaconate + NH3
-
6056
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
r
6056
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6056
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6056
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6056
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
-
6056
Clostridium tetanomorphum
?
-
-
-
-