BRENDA - Enzyme Database

Substrate specificity of the 3-methylaspartate ammonia-lyase reaction: Observation of differential relative reaction rates for substrate-product pairs

Botting, N.P.; Akhtar, M.; Cohen, M.A.; Gani, D.; Biochemistry 27, 2953-2955 (1988)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.3.1.2
L-threo-3-methylaspartate
Clostridium tetanomorphum
-
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.3.1.2
Clostridium tetanomorphum
-
; ATCC 15920
-
4.3.1.2
Clostridium tetanomorphum H1 / ATCC 15920
-
-
-
Reaction
EC Number
Reaction
Commentary
Organism
4.3.1.2
L-threo-3-methylaspartate = mesaconate + NH3
mechanism; stereochemical mechanism
Clostridium tetanomorphum
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.3.1.2
beta-ethylaspartate
3-ethylaspartic acid
6055
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
beta-ethylaspartate
3-ethylaspartic acid
6055
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
4.3.1.2
erythro-3-methylaspartate
-
6055
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
erythro-3-methylaspartate
-
6055
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
4.3.1.2
ethylfumarate + NH3
-
6055
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
iso-propylfumarate + NH3
-
6055
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
L-aspartate
rate of deamination 100 times slower than that of L-threo-3-methylaspartate
6055
Clostridium tetanomorphum
fumarate + NH3
-
6055
Clostridium tetanomorphum
-
4.3.1.2
L-aspartate
rate of deamination 100 times slower than that of L-threo-3-methylaspartate
6055
Clostridium tetanomorphum H1 / ATCC 15920
fumarate + NH3
-
6055
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
r
6055
Clostridium tetanomorphum
mesaconate + NH3
-
6055
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6055
Clostridium tetanomorphum
mesaconate + NH3
-
6055
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
r
6055
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6055
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6055
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6055
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
-
6055
Clostridium tetanomorphum
?
-
-
-
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.3.1.2
L-threo-3-methylaspartate
Clostridium tetanomorphum
-
?
-
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.3.1.2
beta-ethylaspartate
3-ethylaspartic acid
6055
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
beta-ethylaspartate
3-ethylaspartic acid
6055
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
4.3.1.2
erythro-3-methylaspartate
-
6055
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
erythro-3-methylaspartate
-
6055
Clostridium tetanomorphum H1 / ATCC 15920
?
-
-
-
-
4.3.1.2
ethylfumarate + NH3
-
6055
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
iso-propylfumarate + NH3
-
6055
Clostridium tetanomorphum
?
-
-
-
-
4.3.1.2
L-aspartate
rate of deamination 100 times slower than that of L-threo-3-methylaspartate
6055
Clostridium tetanomorphum
fumarate + NH3
-
6055
Clostridium tetanomorphum
-
4.3.1.2
L-aspartate
rate of deamination 100 times slower than that of L-threo-3-methylaspartate
6055
Clostridium tetanomorphum H1 / ATCC 15920
fumarate + NH3
-
6055
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
r
6055
Clostridium tetanomorphum
mesaconate + NH3
-
6055
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6055
Clostridium tetanomorphum
mesaconate + NH3
-
6055
Clostridium tetanomorphum
-
4.3.1.2
L-threo-3-methylaspartate
r
6055
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6055
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
(2S,3S)-3-methylaspartic acid
6055
Clostridium tetanomorphum H1 / ATCC 15920
mesaconate + NH3
-
6055
Clostridium tetanomorphum H1 / ATCC 15920
-
4.3.1.2
L-threo-3-methylaspartate
-
6055
Clostridium tetanomorphum
?
-
-
-
-