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Literature summary extracted from

  • Akhtar, M.; Cohen, M.A.; Gani, D.
    Enzymic synthesis of 3-halogenoaspartic acids using beta-methylaspartase: Inhibition by 3-bromoaspartic acid (1980), J. Chem. Soc. Chem. Commun., 1986, 1290-1291.
No PubMed abstract available

Application

EC Number Application Comment Organism
4.3.1.2 synthesis enzyme is used for L-aspartic acid production Clostridium tetanomorphum

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.1.2 3-bromoaspartate irreversible Clostridium tetanomorphum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.3.1.2 L-threo-3-methylaspartate Clostridium tetanomorphum
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.2 Clostridium tetanomorphum
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
4.3.1.2 L-threo-3-methylaspartate = mesaconate + NH3 mechanism Clostridium tetanomorphum
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.2 3-bromoaspartate
-
 Clostridium tetanomorphum bromofumarate + NH3 during reaction, enzyme becomes inactive. This is reduced in the presence of alternative substrates ?
4.3.1.2 3-chloroaspartate
-
 Clostridium tetanomorphum chlorofumarate + NH3
-
 ?
4.3.1.2 L-aspartate (2S)-aspartate Clostridium tetanomorphum fumarate + NH3
-
 ?
4.3.1.2 L-threo-3-methylaspartate r Clostridium tetanomorphum mesaconate + NH3
-
 ?
4.3.1.2 L-threo-3-methylaspartate (2S,3S)-3-methylaspartic acid Clostridium tetanomorphum mesaconate + NH3
-
 ?
4.3.1.2 L-threo-3-methylaspartate
-
 Clostridium tetanomorphum ?
-
 ?