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Literature summary extracted from

  • Thomas, J.H.; Tudball, N.
    Studies on the enzymic degradation of L-serine O-sulphate by a rat liver preparation (1967), Biochem. J., 105, 467-472.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.1.10 D-serine O-sulfate 10 mM: 19% inhibition Rattus norvegicus
4.3.1.10 DL-homoserine O-sulfate 10 mM: 11% inhibition Rattus norvegicus
4.3.1.10 hydrazine hydrochloride 1 mM: 15% inhibition Rattus norvegicus
4.3.1.10 Hydroxylamine hydrochloride 0.1 mM: 8% inhibition, 1 mM: 13% inhibiotion Rattus norvegicus
4.3.1.10 iodoacetic acid 0.01 mM: 17% inhibition, 0.1 mM: 76% inhibition, 1 mM: 95% inhibition Rattus norvegicus
4.3.1.10 additional information
-
 Rattus norvegicus
4.3.1.10 O-acetyl-L-serine 4 mM: 53% inhibition, 10 mM: 96% inhibition; potent non-competitive Rattus norvegicus
4.3.1.10 O-phospho-L-serine 5 mM: 44% inhibition, 10 mM: 98% inhibition; potent non-competitive Rattus norvegicus
4.3.1.10 p-chloromercuribenzoate 0.01 mM: 18% inhibition, 0.1 mM: 61% inhibition, 1 mM. 94% inhibition Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.1.10 2.3
-
 L-serine O-sulfate
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.10 Rattus norvegicus
-
 male M.R.C. hooded rat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.3.1.10
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.3.1.10 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.3.1.10 additional information
-
-
 Rattus norvegicus
4.3.1.10 1.48
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
4.3.1.10 -20°C, stable for several weeks Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.10 beta-chloroalanine beta-chloro-L-alanine Rattus norvegicus ?
-
 ?
4.3.1.10 D-serine-O-sulfate
-
 Rattus norvegicus pyruvate + NH3 + SO42-
-
 ?
4.3.1.10 L-serine O-sulfate
-
 Rattus norvegicus pyruvate + NH3 + sulfate
-
 ?
4.3.1.10 L-seryl-glycine O-sulfate
-
 Rattus norvegicus ?
-
 ?
4.3.1.10 L-seryl-L-alanine O-sulfate
-
 Rattus norvegicus ?
-
 ?
4.3.1.10 L-seryl-L-leucine O-sulfate
-
 Rattus norvegicus ?
-
 ?
4.3.1.10 L-seryl-L-phenylalanine O-sulfate
-
 Rattus norvegicus ?
-
 ?
4.3.1.10 L-seryl-L-valine O-sulfate
-
 Rattus norvegicus ?
-
 ?
4.3.1.10 L-threonine O-sulfate
-
 Rattus norvegicus 2-oxobutanoate + NH3 + SO42-
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.3.1.10 37
-
 enzyme assay at Rattus norvegicus