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Literature summary extracted from
- Kinetic studies of L-aspartase from Escherichia coli: pH-dependent activity changes (1991), Arch. Biochem. Biophys., 287, 60-67.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.3.1.1 | 3-nitropropionate | competitive | Escherichia coli |  |
| 4.3.1.1 | dimethyl sulfoxide | nonspecific | Escherichia coli | |
| 4.3.1.1 | DL-2-amino-4-phosphonobutyrate | competitive | Escherichia coli | |
| 4.3.1.1 | ethanol | moderate, nonspecific | Escherichia coli | |
| 4.3.1.1 | methanol | moderate, nonspecific | Escherichia coli | |
| 4.3.1.1 | additional information | - |
Escherichia coli | |
| 4.3.1.1 | succinate | competitive | Escherichia coli | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.3.1.1 | Ca2+ | - |
Escherichia coli | |
| 4.3.1.1 | Mg2+ | - |
Escherichia coli | |
| 4.3.1.1 | Mg2+ | - |
Hafnia alvei | |
| 4.3.1.1 | additional information | - |
Hafnia alvei | |
| 4.3.1.1 | additional information | absolute requirement for divalent metal ion at high pH value | Escherichia coli |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.3.1.1 | Escherichia coli | - |
- |
- |
| 4.3.1.1 | Hafnia alvei | - |
- |
- |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 4.3.1.1 | L-aspartate = fumarate + NH3 | mechanism | Escherichia coli |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.3.1.1 | additional information | - |
- |
Escherichia coli |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.3.1.1 | fumarate + hydroxylamine | fumarate | Escherichia coli | ? | - |
? | |
| 4.3.1.1 | L-aspartate | r | Escherichia coli | fumarate + NH3 | - |
? | |
| 4.3.1.1 | L-aspartate | r | Hafnia alvei | fumarate + NH3 | - |
? | |
| 4.3.1.1 | L-aspartate | natural substrate | Escherichia coli | fumarate + NH3 | - |
? | |
| 4.3.1.1 | L-aspartate | natural substrate | Hafnia alvei | fumarate + NH3 | - |
? | |
| 4.3.1.1 | additional information | - |
Escherichia coli | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.3.1.1 | additional information | - |
- |
Escherichia coli |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.3.1.1 | additional information | - |
- |
Escherichia coli |
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Release 2023.1 (January 2023)
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