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Literature summary extracted from

  • Tanaka, M.; Izumi, Y.; Yamada, H.
    Microbial metabolism and production of biotin (1988), Vitamins (Kyoto), 62, 305-315.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.2.1.11 1,10-phenanthroline
-
 Mycoplana sp.
6.2.1.11 Cu2+
-
 Mycoplana sp.
6.2.1.11 EDTA
-
 Mycoplana sp.
6.2.1.11 Fe3+
-
 Mycoplana sp.
6.2.1.11 Hg2+
-
 Mycoplana sp.
6.2.1.11 iodoacetic acid
-
 Mycoplana sp.
6.2.1.11 Ni2+
-
 Mycoplana sp.
6.2.1.11 p-chloromercuribenzoate
-
 Mycoplana sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.11 0.15
-
 CoA
-
 Mycoplana sp.
6.2.1.11 0.3
-
 (+/-)-dethiobiotin
-
 Mycoplana sp.
6.2.1.11 0.32
-
 (+)-biotin
-
 Mycoplana sp.
6.2.1.11 0.43
-
 DL-actithiazic acid
-
 Mycoplana sp.
6.2.1.11 1.3
-
 5-(2-thienyl)-n-valerate
-
 Mycoplana sp.
6.2.1.11 2.8
-
 ATP
-
 Mycoplana sp.

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.2.1.11 Mg2+ required Mycoplana sp.
6.2.1.11 Mn2+ 61% of the activation relative to Mg2+ Mycoplana sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.2.1.11 55000 57000
-
 Mycoplana sp.

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.11 Mycoplana sp.
-
 No. 166
-
6.2.1.11 Mycoplana sp. No. 166
-
 No. 166
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.2.1.11
-
 Mycoplana sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.11 ATP + (+/-)-dethiobiotin + CoA
-
 Mycoplana sp. AMP + diphosphate + dethiobiotinyl-CoA
-
 ?
6.2.1.11 ATP + (+/-)-dethiobiotin + CoA
-
 Mycoplana sp. No. 166 AMP + diphosphate + dethiobiotinyl-CoA
-
 ?
6.2.1.11 ATP + 5-(2-thienyl)-n-valerate + CoA
-
 Mycoplana sp. AMP + diphosphate + 5-(2-thienyl)-n-valeryl-CoA
-
 ?
6.2.1.11 ATP + 5-(2-thienyl)-n-valerate + CoA
-
 Mycoplana sp. No. 166 AMP + diphosphate + 5-(2-thienyl)-n-valeryl-CoA
-
 ?
6.2.1.11 ATP + actithiazic acid + CoA
-
 Mycoplana sp. AMP + diphosphate + actithiazyl-CoA
-
 ?
6.2.1.11 ATP + actithiazic acid + CoA
-
 Mycoplana sp. No. 166 AMP + diphosphate + actithiazyl-CoA
-
 ?
6.2.1.11 ATP + biotin + CoA highly specific for ATP Mycoplana sp. AMP + diphosphate + biotinyl-CoA
-
 ?
6.2.1.11 ATP + biotin + CoA highly specific for ATP Mycoplana sp. No. 166 AMP + diphosphate + biotinyl-CoA
-
 ?
6.2.1.11 ATP + dethiobiotin + CoA 52% of the activity relative to biotin Mycoplana sp. AMP + diphosphate + dethiobiotinyl-CoA
-
 ?
6.2.1.11 ATP + dethiobiotin + CoA 52% of the activity relative to biotin Mycoplana sp. No. 166 AMP + diphosphate + dethiobiotinyl-CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
6.2.1.11 monomer
-
 Mycoplana sp.

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
6.2.1.11 35
-
-
 Mycoplana sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.2.1.11 8.5
-
-
 Mycoplana sp.

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
6.2.1.11 6.5 8.5 25°C, 1 h, stable Mycoplana sp.