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Literature summary extracted from

  • Matsushita, T.; Davis, F.F.
    Studies on pseudouridylic acid synthetase from various sources (1971), Biochim. Biophys. Acta, 238, 165-173.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.70 p-chloromercuribenzoate
-
 Agrobacterium tumefaciens
4.2.1.70 p-chloromercuribenzoate
-
 Nicotiana glauca

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.70 Agrobacterium tumefaciens
-
 B6-6 (ATCC)
-
4.2.1.70 Agrobacterium tumefaciens B6-6
-
 B6-6 (ATCC)
-
4.2.1.70 Bos taurus
-
 calf
-
4.2.1.70 Brassica oleracea
-
 var. italica
-
4.2.1.70 Lolium perenne
-
 rye grass
-
4.2.1.70 Nicotiana glauca
-
 normal and with Agrobacterium tumefaciens transformed tissue
-
4.2.1.70 Saccharomyces cerevisiae
-
-
-
4.2.1.70 Spinacia oleracea
-
 spinach
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.70 stem
-
 Nicotiana glauca
-
4.2.1.70 thymus
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.70 additional information
-
-
 Saccharomyces cerevisiae
4.2.1.70 additional information
-
-
 Agrobacterium tumefaciens
4.2.1.70 additional information
-
-
 Nicotiana glauca

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.70 uracil + D-ribose 5-phosphate
-
 Saccharomyces cerevisiae pseudouridine 5'-phosphate + H2O
-
 ?
4.2.1.70 uracil + D-ribose 5-phosphate
-
 Bos taurus pseudouridine 5'-phosphate + H2O
-
 ?
4.2.1.70 uracil + D-ribose 5-phosphate
-
 Spinacia oleracea pseudouridine 5'-phosphate + H2O
-
 ?
4.2.1.70 uracil + D-ribose 5-phosphate
-
 Brassica oleracea pseudouridine 5'-phosphate + H2O
-
 ?
4.2.1.70 uracil + D-ribose 5-phosphate
-
 Lolium perenne pseudouridine 5'-phosphate + H2O
-
 ?
4.2.1.70 uracil + D-ribose 5-phosphate r Agrobacterium tumefaciens pseudouridine 5'-phosphate + H2O
-
 ?
4.2.1.70 uracil + D-ribose 5-phosphate r Nicotiana glauca pseudouridine 5'-phosphate + H2O
-
 ?
4.2.1.70 uracil + D-ribose 5-phosphate r Agrobacterium tumefaciens B6-6 pseudouridine 5'-phosphate + H2O
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.2.1.70 30
-
-
 Nicotiana glauca

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.2.1.70 10 50 about 40% of maximal activity at 10°C and about 10% of maximal activity at 50°C Nicotiana glauca

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2.1.70 8.5
-
-
 Nicotiana glauca

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.2.1.70 7.5 10 pH 7.5 about 40% of maximal activity, pH 10 about 20% of maximal activity Nicotiana glauca