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Literature summary extracted from

  • Guranowski, A.; Gunther Sillero, M.A.; Sillero, A.
    Adenosine 5'-tetraphosphate and adenosine 5'-pentaphosphate are synthesized by yeast acetyl coenzyme A synthetase (1994), J. Bacteriol., 176, 2986-2990.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.2.1.1 acetate stimulates adenosine 5´-tetraphosphate synthesis Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.2.1.1 palmitoyl-CoA noncompetitive with respect to both acetate and CoA , inhibits adenosine 5´-tetraphosphate synthesis Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.1 0.16
-
 ATP synthesis of adenosine 5´-tetraphosphate Saccharomyces cerevisiae
6.2.1.1 1.8
-
 acetyl-CoA
-
 Saccharomyces cerevisiae
6.2.1.1 4.7
-
 tripolyphosphate synthesis of adenosine 5´-tetraphosphate Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.2.1.1 additional information Saccharomyces cerevisiae may contribute to the adenosine 5'-tetraphosphate synthesis and adenosine 5'-pentaphosphate synthesis during yeast sporulation ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.1 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.1 ATP + acetate + CoA
-
 Saccharomyces cerevisiae AMP + diphosphate + acetyl-CoA
-
 ?
6.2.1.1 ATP + tetrapolyphosphate
-
 Saccharomyces cerevisiae adenosine 5'-pentaphosphate
-
 ?
6.2.1.1 ATP + tripolyphosphate
-
 Saccharomyces cerevisiae adenosine 5'-tetraphosphate
-
 ?
6.2.1.1 additional information may contribute to the adenosine 5'-tetraphosphate synthesis and adenosine 5'-pentaphosphate synthesis during yeast sporulation Saccharomyces cerevisiae ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.2.1.1 6.3
-
 adenosine tetraphosphate synthesis Saccharomyces cerevisiae