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Literature summary extracted from
- Enzymatic formation of cis-homoaconitic acid, an intermediate in lysine biosynthesis in yeast (1966), J. Biol. Chem., 241, 5401-5407.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.36 | 1,10-phenanthroline | - |
Saccharomyces cerevisiae |  |
| 4.2.1.36 | 2,2'-dipyridyl | - |
Saccharomyces cerevisiae | |
| 4.2.1.36 | p-chloromercuribenzoate | - |
Saccharomyces cerevisiae | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.36 | Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.36 | 2-hydroxybutane-1,2,4-tricarboxylate | - |
Saccharomyces cerevisiae | but-1-ene-1,2,4-tricarboxylate + H2O | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.36 | 8.6 | - |
phosphate buffer | Saccharomyces cerevisiae |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.36 | 7 | 9 | pH 7.0: about 35% of maximal activity, pH 9.0: about 95% of maximal activity | Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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