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Literature summary extracted from

  • Toraya, T.; Shirakashi, T.; Kosuga, T.; Fukui, S.
    Substrate specificity of coenzyme B12-dependent diol dehydrase: glycerol as both a good substrate and a potent inactivator (1976), Biochem. Biophys. Res. Commun., 69, 475-480.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.28 glycerol
-
 Klebsiella pneumoniae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.28 0.18
-
 1,2-propanediol both cytosolic and membrane associated enzymes Klebsiella pneumoniae
4.2.1.28 0.64
-
 2,3-Butanediol
-
 Klebsiella pneumoniae
4.2.1.28 1.08
-
 1,2-ethanediol both cytosolic and membrane associated enzymes Klebsiella pneumoniae
4.2.1.28 1.54
-
 glycerol cytosolic and membrane-associated enzymes Klebsiella pneumoniae

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.28 Klebsiella pneumoniae
-
 formerly Aerobacter aerogenes
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.28 1,2-butanediol
-
 Klebsiella pneumoniae butyraldehyde
-
 ?
4.2.1.28 1,2-ethanediol
-
 Klebsiella pneumoniae acetaldehyde
-
 ?
4.2.1.28 1,2-propanediol
-
 Klebsiella pneumoniae propanal
-
 ?
4.2.1.28 2,3-butanediol
-
 Klebsiella pneumoniae methyl ethyl ketone
-
 ?
4.2.1.28 glycerol
-
 Klebsiella pneumoniae beta-hydroxypropionaldehyde
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.2.1.28 7.2
-
 1,2-Butanediol
-
 Klebsiella pneumoniae
4.2.1.28 15.1
-
 2,3-Butanediol
-
 Klebsiella pneumoniae
4.2.1.28 286
-
 1,2-ethanediol
-
 Klebsiella pneumoniae
4.2.1.28 337
-
 1,2-propanediol
-
 Klebsiella pneumoniae
4.2.1.28 371
-
 glycerol
-
 Klebsiella pneumoniae

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.1.28 cobamide
-
 Klebsiella pneumoniae