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Literature summary extracted from

  • Ono, B.I.; Kijima, K.; Inoue, T.; Miyoshi, A.I.; Matsuda, A.; Shinoda, S.
    Purification and properties of Saccharomyces cerevisiae cystathionine beta-synthase (1994), Yeast, 10, 333-339.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.22 hydroxylamine
-
 Saccharomyces cerevisiae
4.2.1.22 iodoacetate
-
 Saccharomyces cerevisiae
4.2.1.22 p-chloromercuribenzoate
-
 Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.22 2.19
-
 L-Ser
-
 Saccharomyces cerevisiae
4.2.1.22 2.25
-
 homocysteine
-
 Saccharomyces cerevisiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.22 55000
-
 4 * 55000, SDS-PAGE Saccharomyces cerevisiae
4.2.1.22 235000
-
 gel filtration Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.22 L-Serine + homocysteine Saccharomyces cerevisiae reverse trans-sulfuration pathway ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.22 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.22
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.22 L-Serine + homocysteine
-
 Saccharomyces cerevisiae Cystathionine + H2O
-
 ?
4.2.1.22 L-Serine + homocysteine reverse trans-sulfuration pathway Saccharomyces cerevisiae ?
-
 ?

Subunits

EC Number Subunits Comment Organism
4.2.1.22 tetramer 4 * 55000, SDS-PAGE Saccharomyces cerevisiae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.2.1.22 33
-
-
 Saccharomyces cerevisiae

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.2.1.22 7.38
-
 homocysteine
-
 Saccharomyces cerevisiae
4.2.1.22 7.97
-
 L-Ser
-
 Saccharomyces cerevisiae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2.1.22 7.5
-
-
 Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.1.22 pyridoxal 5'-phosphate requirement Saccharomyces cerevisiae
4.2.1.22 S-adenosyl-L-methionine activation Saccharomyces cerevisiae