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Literature summary extracted from

  • Mano, J.; Hatano, M.; Koizumi, S.; Tada, S.; Hashimoto, M.; Scheidegger, A.
    Purification and properties of a monofunctional imidazoleglycerol-phosphate dehydratase from wheat (1993), Plant Physiol., 103, 733-739.
    View publication on PubMedView publication on EuropePMC

General Stability

EC Number General Stability Organism
4.2.1.19 -80°C, 20 mM triethanolamine-HCl buffer, pH 7.5, 100 mM 2-mercaptoethanol Triticum aestivum

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.19 3-Amino-1,2,4-triazole
-
 Triticum aestivum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.19 0.4
-
 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Triticum aestivum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.1.19 Mn2+ 0.5 mM enhances the activity 7fold Triticum aestivum
4.2.1.19 additional information not activated by Mg2+, Ni2+, Cd2+, Fe2+, Co2+, Fe3+ Triticum aestivum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.19 25000
-
 x * 25000, subunits not linked by disulfide bridges, SDS-PAGE Triticum aestivum
4.2.1.19 600000
-
 gel filtration Triticum aestivum
4.2.1.19 670000
-
 gel electrophoresis Triticum aestivum

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.19 Brassica oleracea
-
 cabbage
-
4.2.1.19 Hordeum vulgare
-
 barley
-
4.2.1.19 Oryza sativa
-
 rice
-
4.2.1.19 Rosa sp.
-
 rose
-
4.2.1.19 Triticum aestivum
-
 wheat
-
4.2.1.19 Zea mays
-
 corn
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.19
-
 Triticum aestivum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.19 germ
-
 Triticum aestivum
-
4.2.1.19 germ
-
 Oryza sativa
-
4.2.1.19 shoot
-
 Hordeum vulgare
-
4.2.1.19 shoot
-
 Zea mays
-
4.2.1.19 shoot
-
 Brassica oleracea
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.19 5.7
-
-
 Triticum aestivum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.19 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Triticum aestivum 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O
-
 ?
4.2.1.19 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Hordeum vulgare 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O
-
 ?
4.2.1.19 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Zea mays 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O
-
 ?
4.2.1.19 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Brassica oleracea 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O
-
 ?
4.2.1.19 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Oryza sativa 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O
-
 ?
4.2.1.19 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Rosa sp. 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
4.2.1.19 polymer x * 25000, subunits not linked by disulfide bridges, SDS-PAGE Triticum aestivum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2.1.19 6.5 7
-
 Triticum aestivum