Literature summary extracted from

Hountondji, C.; Schmitter, J.M.; Fukui, T.; Tagaya, M.; Blanquet, S.
Affinity labeling of aminoacyl-tRNA synthetases with adenosine triphosphopyridoxal. Probing the Lys-Met-Ser-Lys-Ser signature sequence as the ATP-binding site in Escherichia coli methionyl- and valyl-tRNA synthetases (1990), Biochemistry, 29, 11266-11273.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
6.1.1.9	pyridoxal 5'-triphospho-5'-adenosine	aminoacylation and ATP-diphosphate exchange abolished	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.1.1.9	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.1.1.9	ATP + L-valine + tRNAVal	-	Escherichia coli	AMP + diphosphate + L-valyl-tRNAVal	-	?
6.1.1.9	additional information	valine-dependent ATP-diphosphate exchange: valine + ATP + enzyme /Val-AMP-enzyme + diphosphate	Escherichia coli	?	-	?

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Release 2023.1 (January 2023)