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Literature summary extracted from

  • Van Rooijen, R.J.; van Schalkwijk, S.; de Vos, W.M.
    Molecular cloning, characterization, and nucleotide sequence of the tagatose 6-phosphate pathway gene cluster of the lactose operon of Lactose operon of Lactococcus lactis (1991), J. Biol. Chem., 266, 7176-7181.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.144 expression in Escherichia coli Lactobacillus delbrueckii subsp. lactis
4.1.2.40
-
Lactococcus lactis
5.3.1.26 expression of both lacA and lacB is required to obtain galactose-6-phosphate isomerase activity Lactococcus lactis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.2.40 36476
-
x * 36476, calculation from nucleotide sequence Lactococcus lactis
5.3.1.26 15000
-
x * 15000 + x * 19000, SDS-PAGE Lactococcus lactis
5.3.1.26 19000
-
x * 15000 + x * 19000, SDS-PAGE Lactococcus lactis

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.144 Lactobacillus delbrueckii subsp. lactis
-
subsp. lactis MG1820
-
4.1.2.40 Lactococcus lactis
-
subsp. lactis MG1820
-
5.3.1.26 Lactococcus lactis
-
subsp. lactis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.144 ATP + D-tagatose 6-phosphate
-
Lactobacillus delbrueckii subsp. lactis ADP + D-tagatose 1,6-bisphosphate
-
?
4.1.2.40 D-Tagatose-1,6-bisphosphate
-
Lactococcus lactis Glycerone phosphate + D-glyceraldehyde 3-phosphate
-
?
5.3.1.26 D-Galactose 6-phosphate
-
Lactococcus lactis D-Tagatose 6-phosphate
-
?

Subunits

EC Number Subunits Comment Organism
4.1.2.40 ? x * 36476, calculation from nucleotide sequence Lactococcus lactis
5.3.1.26 ? x * 15000 + x * 19000, SDS-PAGE Lactococcus lactis