BRENDA - Enzyme Database show

Isolation and characterization of the mouse P450 17alpha-Hydrolase/C17-20-lyase gene (Cyp 17): Transcriptional regulation of the gene by cyclic adenosine 3¦,5¦-monophosphate in MA-10 Leydig cells

Youngblood, G.L.; Payne, A.; Mol. Endocrinol. 6, 927-934 (1992)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
1.14.14.32
gene encoding cytochrome P450 17alpha-hydrolase/C17-20-lyase (P450 17alpha)
Mus musculus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.14.14.32
Mus musculus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
5128
Mus musculus
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
androstenedione
5128
Mus musculus
-
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
5128
Mus musculus
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
immediate precursor of testosterone
5128
Mus musculus
-
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
1.14.14.32
gene encoding cytochrome P450 17alpha-hydrolase/C17-20-lyase (P450 17alpha)
Mus musculus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
5128
Mus musculus
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
androstenedione
5128
Mus musculus
-
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
5128
Mus musculus
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
immediate precursor of testosterone
5128
Mus musculus
-