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Literature summary extracted from

  • Youngblood, G.L.; Payne, A.
    Isolation and characterization of the mouse P450 17alpha-Hydrolase/C17-20-lyase gene (Cyp 17): Transcriptional regulation of the gene by cyclic adenosine 3¦,5¦-monophosphate in MA-10 Leydig cells (1992), Mol. Endocrinol., 6, 927-934.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.32 gene encoding cytochrome P450 17alpha-hydrolase/C17-20-lyase (P450 17alpha) Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.32 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.32 17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
Mus musculus androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O androstenedione ?
1.14.14.32 17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
Mus musculus androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O immediate precursor of testosterone ?