BRENDA - Enzyme Database show

Rainbow trout cytochrome P-450 c17 (17alpha-hydroxylase/17,20-lyase)

Sakai, N.; Tanaka, M.; Adachi, S.; Miller, W.L.; Nagahama, Y.; FEBS Lett. 30, 60-64 (1992)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
1.14.14.32
full length cDNA clone encoding cytochrome P-450c17 (17alpha-hydrolase/17,20 lyase), expression in mammalian COS-1 cells
Oncorhynchus mykiss
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.14.14.32
additional information
Oncorhynchus mykiss
cytochrome P-450c17 mediates both 17alpha-hydroxylase and 17,20 lyase activities in the synthesis of steroid hormones
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.14.14.32
Oncorhynchus mykiss
-
rainbow trout
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.14.14.32
ovarian follicle
ovarian
Oncorhynchus mykiss
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.14.32
17alpha-Hydroxypregnenolone
-
5127
Oncorhynchus mykiss
Dehydroepiandrosterone + acetaldehyde
DHEA
5127
Oncorhynchus mykiss
-
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
5127
Oncorhynchus mykiss
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
-
5127
Oncorhynchus mykiss
-
1.14.14.32
additional information
cytochrome P-450c17 mediates both 17alpha-hydroxylase and 17,20 lyase activities in the synthesis of steroid hormones
5127
Oncorhynchus mykiss
?
-
-
-
-
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
1.14.14.32
full length cDNA clone encoding cytochrome P-450c17 (17alpha-hydrolase/17,20 lyase), expression in mammalian COS-1 cells
Oncorhynchus mykiss
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.14.14.32
additional information
Oncorhynchus mykiss
cytochrome P-450c17 mediates both 17alpha-hydroxylase and 17,20 lyase activities in the synthesis of steroid hormones
?
-
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.14.14.32
ovarian follicle
ovarian
Oncorhynchus mykiss
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.14.32
17alpha-Hydroxypregnenolone
-
5127
Oncorhynchus mykiss
Dehydroepiandrosterone + acetaldehyde
DHEA
5127
Oncorhynchus mykiss
-
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
5127
Oncorhynchus mykiss
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
-
5127
Oncorhynchus mykiss
-
1.14.14.32
additional information
cytochrome P-450c17 mediates both 17alpha-hydroxylase and 17,20 lyase activities in the synthesis of steroid hormones
5127
Oncorhynchus mykiss
?
-
-
-
-