BRENDA - Enzyme Database show

Bioconversion of steroids in vitro by testes from autoimmunized rabbits

Nowotny, E.; Sananez, R.D.; Nattero, G.; Hoppe-Seyler's Z. Physiol. Chem. 355, 716-720 (1974)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.14.14.32
additional information
Oryctolagus cuniculus
enzyme of the biosynthetic pathway for testosterone synthesis. Impairment of the reaction occurs in autoimmunized rabbits with severe damage of testes
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.14.14.32
Oryctolagus cuniculus
-
New Zealand rabbit
-
Reaction
EC Number
Reaction
Commentary
Organism
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2 = androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
bioconversion in vitro
Oryctolagus cuniculus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.14.14.32
testis
-
Oryctolagus cuniculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
5125
Oryctolagus cuniculus
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
-
5125
Oryctolagus cuniculus
-
1.14.14.32
additional information
enzyme of the biosynthetic pathway for testosterone synthesis. Impairment of the reaction occurs in autoimmunized rabbits with severe damage of testes
5125
Oryctolagus cuniculus
?
-
-
-
-
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
1.14.14.32
37
-
assay at
Oryctolagus cuniculus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.14.14.32
additional information
Oryctolagus cuniculus
enzyme of the biosynthetic pathway for testosterone synthesis. Impairment of the reaction occurs in autoimmunized rabbits with severe damage of testes
?
-
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.14.14.32
testis
-
Oryctolagus cuniculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.14.32
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
5125
Oryctolagus cuniculus
androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
-
5125
Oryctolagus cuniculus
-
1.14.14.32
additional information
enzyme of the biosynthetic pathway for testosterone synthesis. Impairment of the reaction occurs in autoimmunized rabbits with severe damage of testes
5125
Oryctolagus cuniculus
?
-
-
-
-
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
1.14.14.32
37
-
assay at
Oryctolagus cuniculus