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Literature summary extracted from

  • Nowotny, E.; Sananez, R.D.; Nattero, G.
    Bioconversion of steroids in vitro by testes from autoimmunized rabbits (1974), Hoppe-Seyler's Z. Physiol. Chem., 355, 716-720.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.32 additional information Oryctolagus cuniculus enzyme of the biosynthetic pathway for testosterone synthesis. Impairment of the reaction occurs in autoimmunized rabbits with severe damage of testes ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.32 Oryctolagus cuniculus
-
 New Zealand rabbit
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.14.14.32 17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2 = androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O bioconversion in vitro Oryctolagus cuniculus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.32 testis
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.32 17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryctolagus cuniculus androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.32 additional information enzyme of the biosynthetic pathway for testosterone synthesis. Impairment of the reaction occurs in autoimmunized rabbits with severe damage of testes Oryctolagus cuniculus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.14.14.32 37
-
 assay at Oryctolagus cuniculus