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Literature summary extracted from
- Phosphoketolase in Rhodotorula graminis and other yeasts (1977), J. Gen. Microbiol., 102, 397-401.
No PubMed abstract available
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.2.9 | phosphate | required | Rhodotorula graminis |  |
| 4.1.2.9 | phosphate | Km: 5.55 mM | Rhodotorula graminis | |
| 4.1.2.22 | thiamin diphosphate | required | Rhodotorula graminis | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.2.9 | acetyl-CoA | - |
Rhodotorula graminis | |
| 4.1.2.9 | ATP | - |
Rhodotorula graminis | |
| 4.1.2.9 | citrate | - |
Rhodotorula graminis | |
| 4.1.2.9 | dodecanoyl-CoA | - |
Rhodotorula graminis | |
| 4.1.2.9 | NADH | - |
Rhodotorula graminis | |
| 4.1.2.9 | NADPH | - |
Rhodotorula graminis | |
| 4.1.2.9 | phosphoenolpyruvate | - |
Rhodotorula graminis | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.2.9 | 1.25 | - |
D-xylulose 5-phosphate | - |
Rhodotorula graminis | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.2.9 | Mg2+ | required, Km: 0.000395 mM | Rhodotorula graminis | |
| 4.1.2.22 | Mg2+ | required | Rhodotorula graminis | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.2.9 | additional information | Rhodotorula graminis | contribution of phosphoketolase to glucose catabolism is only slight | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.2.9 | Candida sp. (in: Saccharomycetales) | - |
- |
- |
| 4.1.2.9 | Candida sp. (in: Saccharomycetales) 107 | - |
- |
- |
| 4.1.2.9 | Candida tropicalis | - |
- |
- |
| 4.1.2.9 | Rhodotorula glutinis | - |
- |
- |
| 4.1.2.9 | Rhodotorula graminis | - |
- |
- |
| 4.1.2.9 | Vanrija humicola | - |
- |
- |
| 4.1.2.22 | Candida sp. (in: Saccharomycetales) | - |
- |
- |
| 4.1.2.22 | Candida sp. (in: Saccharomycetales) 107 | - |
- |
- |
| 4.1.2.22 | Candida tropicalis | - |
- |
- |
| 4.1.2.22 | Rhodotorula glutinis | - |
- |
- |
| 4.1.2.22 | Rhodotorula graminis | - |
- |
- |
| 4.1.2.22 | Saccharomyces pastorianus | - |
weak | - |
Oxidation Stability
| EC Number | Oxidation Stability | Organism |
|---|---|---|
| 4.1.2.9 | phosphate is essential for stability | Rhodotorula graminis |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.2.9 | - |
Rhodotorula graminis |
| 4.1.2.22 | - |
Rhodotorula graminis |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 4.1.2.9 | 4°C, 24 h, 50% loss of activity | Rhodotorula graminis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.2.9 | D-fructose 6-phosphate + phosphate | - |
Vanrija humicola | ? | - |
? | |
| 4.1.2.9 | D-Xylulose 5-phosphate + phosphate | - |
Rhodotorula glutinis | Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O | - |
? | |
| 4.1.2.9 | D-Xylulose 5-phosphate + phosphate | - |
Candida tropicalis | Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O | - |
? | |
| 4.1.2.9 | D-Xylulose 5-phosphate + phosphate | - |
Rhodotorula graminis | Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O | - |
? | |
| 4.1.2.9 | D-Xylulose 5-phosphate + phosphate | - |
Candida sp. (in: Saccharomycetales) | Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O | - |
? | |
| 4.1.2.9 | D-Xylulose 5-phosphate + phosphate | - |
Vanrija humicola | Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O | - |
? | |
| 4.1.2.9 | D-Xylulose 5-phosphate + phosphate | - |
Candida sp. (in: Saccharomycetales) 107 | Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O | - |
? | |
| 4.1.2.9 | additional information | contribution of phosphoketolase to glucose catabolism is only slight | Rhodotorula graminis | ? | - |
? | |
| 4.1.2.22 | D-Fructose 6-phosphate + phosphate | - |
Saccharomyces pastorianus | Acetyl phosphate + D-erythrose 4-phosphate + H2O | - |
? | |
| 4.1.2.22 | D-Fructose 6-phosphate + phosphate | - |
Rhodotorula glutinis | Acetyl phosphate + D-erythrose 4-phosphate + H2O | - |
? | |
| 4.1.2.22 | D-Fructose 6-phosphate + phosphate | - |
Candida tropicalis | Acetyl phosphate + D-erythrose 4-phosphate + H2O | - |
? | |
| 4.1.2.22 | D-Fructose 6-phosphate + phosphate | - |
Rhodotorula graminis | Acetyl phosphate + D-erythrose 4-phosphate + H2O | - |
? | |
| 4.1.2.22 | D-Fructose 6-phosphate + phosphate | - |
Candida sp. (in: Saccharomycetales) | Acetyl phosphate + D-erythrose 4-phosphate + H2O | - |
? | |
| 4.1.2.22 | D-Fructose 6-phosphate + phosphate | - |
Candida sp. (in: Saccharomycetales) 107 | Acetyl phosphate + D-erythrose 4-phosphate + H2O | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.2.9 | 30 | - |
- |
Rhodotorula graminis |
Temperature Range [°C]
| EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.2.9 | 27.5 | 32.5 | 27.5°C: about 70% of maximal activity, 32.5°C: about 30% of maximal activity | Rhodotorula graminis |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.2.9 | 6 | - |
- |
Rhodotorula graminis |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.2.9 | 5.5 | 7 | about 40% of maximal activity at pH 5.5 and at pH 7.0 | Rhodotorula graminis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.2.9 | thiamine diphosphate | required | Rhodotorula graminis | |
| 4.1.2.9 | thiamine diphosphate | Km: 0.000404 mM | Rhodotorula graminis | |
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