Literature summary extracted from

Yu, P.W.; Huang, B.C.; Shen, M.; Quast, J.; Chan, E.; Xu, X.; Nolan, G.P.; Payan, D.G.; Luo, Y.
Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB (1999), Curr. Biol., 9, 539-542.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.10.2	ATP + a protein	Homo sapiens	enzyme functions as an intermediary in TNFalpha-induced apoptosis	ADP + a phosphoprotein	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.10.2	Homo sapiens	Q9Y572	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.10.2	ATP + a protein	enzyme functions as an intermediary in TNFalpha-induced apoptosis	Homo sapiens	ADP + a phosphoprotein	-	?
2.7.10.2	additional information	activates NF-kappaB	Homo sapiens	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.10.2	receptor interacting protein 3	-	Homo sapiens

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Release 2023.1 (January 2023)