EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.12.2 | additional information | the enzyme is activated in cells treated with tumor necrosis factor-alpha | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.12.2 | ATP + protein | Homo sapiens | ASK1 may be a key element in the mechanism of stress-induced and cytokine-induced apoptosis | ADP + phosphoprotein | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.12.2 | Homo sapiens | Q99683 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.12.2 | heart | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.12.2 | ATP + protein | ASK1 may be a key element in the mechanism of stress-induced and cytokine-induced apoptosis | Homo sapiens | ADP + phosphoprotein | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.12.2 | ASK1 | - |
Homo sapiens |
2.7.12.2 | MAPKKK5 | - |
Homo sapiens |
2.7.12.2 | mitogen-activated protein kinase kinase kinase 5 | - |
Homo sapiens |