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Literature summary extracted from

  • Cairns, B.R.; Ramer, S.W.; Kornberg, R.D.
    Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase (1992), Genes Dev., 6, 1305-1318.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.25 isolation and characterization Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.25 ATP + protein Saccharomyces cerevisiae enzyme is involved in the response of haploid yeast cells to peptide mating pheromones ADP + phosphoprotein
-
 ?
2.7.12.2 ATP + protein Saccharomyces cerevisiae enzyme is involved in the response of haploid yeast cells to peptide mating pheromones ADP + phosphoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.25 Saccharomyces cerevisiae P23561
-
-
2.7.12.2 Saccharomyces cerevisiae P06784
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.12.2 phosphoprotein STE7 displays several phosphorylation forms and is multiply phosphorylated in response to either pheromone or coexpression of dominant STE11 protein Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.25 ATP + protein enzyme is involved in the response of haploid yeast cells to peptide mating pheromones Saccharomyces cerevisiae ADP + phosphoprotein
-
 ?
2.7.12.2 ATP + protein enzyme is involved in the response of haploid yeast cells to peptide mating pheromones Saccharomyces cerevisiae ADP + phosphoprotein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.25 serine/threonine-protein kinase STE11
-
 Saccharomyces cerevisiae
2.7.12.2 serine/threonine protein kinase STE7
-
 Saccharomyces cerevisiae