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Literature summary extracted from

  • Stokoe, D.; Caudwell, B.; Cohen, P.T.; Cohen, P.
    The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2 (1993), Biochem. J., 296, 843-849.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.1
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.1 Homo sapiens P49137
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.1 ATP + Lys-Lys-Phe-Asn-Arg-Thr-Leu-Ser-Val-Ala
-
 Homo sapiens ADP + ?
-
 ?
2.7.11.1 ATP + protein minimum sequence required for efficient phosphorylation is Xaa-Xaa-Hyd-Xaa-Arg-Xaa-Xaa-Ser-Xaa-Xaa, where Hyd is a bulky hydrophobic residue (in decreasing order), Phe, Leu, Val, Ala, MAPKAP kinase-2 can not tolerate a proline residue at position n + 1 Homo sapiens ADP + phosphoprotein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.1 MAP kinase activated protein kinase 2
-
 Homo sapiens
2.7.11.1 MAPKAP kinase-2
-
 Homo sapiens