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Literature summary extracted from

  • Hirayama, I.; Tamemoto, H.; Yokota, H.; Kubo, S.K.; Wang, J.; Kuwano, H.; Nagamachi, Y.; Takeuchi, T.; Izumi, T.
    Insulin receptor-related receptor is expressed in pancreatic beta-cells and stimulates tyrosine phosphorylation of insulin receptor substrate-1 and -2 (1999), Diabetes, 48, 1237-1244.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.10.1 a chimeric receptor consisting of the extracellular domain of insulin receptor and the intracellular domain of IRR is expressed in Chinese hamster ovary cells Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.1 additional information Mus musculus receptor may play a role in the regulation of beta-cell mass ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.1 Mus musculus Q9wtl4
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.1 pancreatic islet
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.1 ATP + protein tyrosine IRS-1 and IRS-2 proteins serve as substrates Mus musculus ADP + protein tyrosine phosphate
-
 ?
2.7.10.1 additional information receptor may play a role in the regulation of beta-cell mass Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.1 insulin receptor-related protein
-
 Mus musculus
2.7.10.1 IRR-protein tyrosine kinase
-
 Mus musculus