EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.14 | 5',5'-P1,P4-diguanosine tetraphosphate | IC50: 0.4 mM, 2 mM, approx. 80% inhibition | Artemia sp. | |
2.4.2.14 | ADP | 1 mM, approx. 95% inhibition | Artemia sp. | |
2.4.2.14 | AMP | 1 mM, approx. 40% inhibition | Artemia sp. | |
2.4.2.14 | GDP | 1 mM, approx. 75% inhibition | Artemia sp. | |
2.4.2.14 | GMP | 1 mM, approx. 60% inhibition | Artemia sp. |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.14 | 0.4 | - |
5-phospho-alpha-D-ribose 1-diphosphate | cosubstrate NH3 | Artemia sp. | |
2.4.2.14 | 0.7 | - |
5-phospho-alpha-D-ribose 1-diphosphate | cosubstrate glutamine | Artemia sp. |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.2.14 | soluble | - |
Artemia sp. | - |
- |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.14 | Artemia sp. | - |
brine shrimp, activity increases 7fold during early larval development in 2 d old Artemia | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.2.14 | partial | Artemia sp. |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.2.14 | nauplius | - |
Artemia sp. | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.14 | L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O | - |
Artemia sp. | 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate | - |
ir | |
2.4.2.14 | NH3 + 5-phospho-alpha-D-ribose 1-diphosphate + H2O | lower aminotransferase activity compared to amidotransferase activity | Artemia sp. | 5-phospho-beta-D-ribosylamine + diphosphate | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.4.2.14 | 37 | - |
assay at | Artemia sp. |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.4.2.14 | 0.4 | - |
IC50: 0.4 mM, 2 mM, approx. 80% inhibition | Artemia sp. | 5',5'-P1,P4-diguanosine tetraphosphate |