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Literature summary extracted from

  • Ishibashi, T.; Atsuta, T.; Makita, A.
    Effects of uridine nucleotides and nucleotide pyrophosphatase on glycolipid alpha and beta-N-acetylgalactosaminyltransferase activities in guinea pig microsomes (1976), Biochim. Biophys. Acta, 429, 759-767.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.88 UDP-glucose slight stimulation Cavia porcellus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.88 PCMB no inhibition Cavia porcellus
2.4.1.88 UDP
-
 Cavia porcellus
2.4.1.88 UDP-galactose
-
 Cavia porcellus
2.4.1.88 UDP-glucose competitive versus UDP-N-acetylgalactosamine; strong Cavia porcellus
2.4.1.88 UDP-N-acetylglucosamine strong Cavia porcellus
2.4.1.88 UMP
-
 Cavia porcellus
2.4.1.88 uridine
-
 Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.88 microsome
-
 Cavia porcellus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.88 UDP-N-acetyl-D-galactosamine + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide Cavia porcellus
-
 UDP + N-acetyl-D-galactosaminyl-1,3-N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide i.e. Forssman hapten ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.88 Cavia porcellus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.88 kidney
-
 Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.88 UDP-N-acetyl-D-galactosamine + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
-
 Cavia porcellus UDP + N-acetyl-D-galactosaminyl-1,3-N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide i.e. Forssman hapten ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.88 37
-
 assay at Cavia porcellus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.88 6.9
-
 assay at Cavia porcellus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.88 0.033
-
 UDP-glucose
-
 Cavia porcellus