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Literature summary extracted from

  • Mercier, D.; Charreau, B.; Wierinckx, A.; Keijser, R.; Adriaensens, L.; Van den Berg, R.; Joziasse, D.H.
    Regulation of alpha1,3galactosyltransferase expression in pig endothelial cells: Implications for xenotransplantation (2002), Eur. J. Biochem., 269, 1464-1473.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.87 expression in COS-7 cells, promotor sequences A-C determination and analysis, gene regulation and regulatory sequences, alternative splicing Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.87 additional information Sus scrofa the alphaGal(1-3)Gal epitope is the major xenoantigen responsible for the hyperacute vascular rejection occurring in pig-to-primate organ transplantation ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.87 Sus scrofa AF415202
-
-
2.4.1.87 Sus scrofa AF415202 TNFalpha inducible
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.87 aorta
-
 Sus scrofa
-
2.4.1.87 endothelium primary and permanent, aortic Sus scrofa
-
2.4.1.87 kidney
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.87 additional information the alphaGal(1-3)Gal epitope is the major xenoantigen responsible for the hyperacute vascular rejection occurring in pig-to-primate organ transplantation Sus scrofa ?
-
 ?
2.4.1.87 UDP-galactose + saccharides containing Galalpha(1-3)Gal epitope
-
 Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.87 alpha-1,3-galactosyltransferase
-
 Sus scrofa
2.4.1.87 alpha1,3GT
-
 Sus scrofa