EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.74 | 2-mercaptoethanol | stimulation | Rattus norvegicus | |
2.4.1.74 | ATP | inhibits at high UDPgalactose concentration, stimulates at low UDPgalactose concentration | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.74 | ATP | inhibits at high UDPgalactose concentration, stimulates at low UDPgalactose concentration | Rattus norvegicus | |
2.4.1.74 | EDTA | inhibits probably due to complex binding to Mn2+ | Rattus norvegicus | |
2.4.1.74 | Triton X-100 | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.1.74 | Golgi membrane | - |
Rattus norvegicus | 139 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.74 | Mn2+ | maximal activation by 5 mM MnCl2 | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.74 | Rattus norvegicus | - |
male albino Sprague-Dawley | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.74 | liver | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.4.1.74 | 0.0076 | - |
- |
Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.74 | UDPgalactose + glycosaminoglycan | desialylated bovine submaxillary mucin type I, ovomucoid, ovalbumin, preferred substrate: desialylated mucin | Rattus norvegicus | UDP + D-galactosylglycosaminoglycan | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.4.1.74 | 7.5 | - |
- |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.4.1.74 | 6.4 | 8 | pH 6.4: about 50% of maximal activity, pH 8.0: about 90% of maximal activity at pH 8.0 | Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.74 | ATP | stimulates at low UDPgalactose concentration, inhibits at high UDPgalactose concentration | Rattus norvegicus |