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Literature summary extracted from

  • Bosmann, H.B.; Eylar, E.H.
    Glycoprotein biosynthesis: the biosynthesis of the hydroxylysine-galactose linkage in collagen (1968), Biochem. Biophys. Res. Commun., 33, 340-346.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.50 EDTA
-
 Cavia porcellus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.50 Co2+
-
 Cavia porcellus
2.4.1.50 Mn2+
-
 Cavia porcellus
2.4.1.50 additional information not activated by Ca2+ Cavia porcellus
2.4.1.50 additional information not activated by Cu2+ Cavia porcellus
2.4.1.50 additional information not activated by Na+ Cavia porcellus
2.4.1.50 additional information not activated by K+, Pb2+ Cavia porcellus
2.4.1.50 additional information not activated by Mg2+ Cavia porcellus
2.4.1.50 additional information not activated by Cd2+ Cavia porcellus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.50 Cavia porcellus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.50 skin, partial Cavia porcellus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.50 cartilage cartilaginous ends of limb bone rudiments Cavia porcellus
-
2.4.1.50 embryo embryo skin Cavia porcellus
-
2.4.1.50 skin embryo skin Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.50 additional information no sugar donor: UDPglucose Cavia porcellus ?
-
 ?
2.4.1.50 additional information no acceptors: galactose, glucose, glucosamine, N-acetylgalactosamine, lysine, hydroxyproline, threonine, serine, fetuin, native guinea pig collagen, glucose-free guinea pig skin collagen, native alpha1-glycoprotein Cavia porcellus ?
-
 ?
2.4.1.50 additional information no acceptor: free hydroxylysine Cavia porcellus ?
-
 ?
2.4.1.50 additional information no sugar donors: UDPxylose, GDPmannose, GDPfucose Cavia porcellus ?
-
 ?
2.4.1.50 UDPgalactose + alpha1-glycoprotein with sialic acid and galactose removed less active than with guinea pig skin collagen with sugar residues removed Cavia porcellus ?
-
 ?
2.4.1.50 UDPgalactose + procollagen 5-hydroxy-L-lysine guinea pig skin collagen with sugar residues removed Cavia porcellus UDP + procollagen 5-(D-galactosyloxy)-L-lysine
-
 ?
2.4.1.50 UDPgalactose + procollagen 5-hydroxy-L-lysine high specificity for galactosyl acceptor Cavia porcellus UDP + procollagen 5-(D-galactosyloxy)-L-lysine
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.50 37
-
 assay at Cavia porcellus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.50 6
-
-
 Cavia porcellus