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Literature summary extracted from

  • Clarke, D.J.; George, S.G.; Burchell, B.
    Multiplicity of UDP-glucuronosyltransferases in fish. Purification and characterization of a phenol UDP-glucuronosyltransferase from the liver of a marine teleost, Pleuronectes platessa (1992), Biochem. J., 284, 417-423.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.17 phosphatidylcholine required by purified preparations for optimal activity Pleuronectes platessa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Pleuronectes platessa
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.17 Mg2+ 30 mM, activation Pleuronectes platessa

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Pleuronectes platessa
-
 plaice
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.17 ammonium sulfate fractionation and affinity chromatography with UDP-hexanolamine Sepharose, several isoforms are isolated Pleuronectes platessa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Pleuronectes platessa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.17 additional information
-
-
 Pleuronectes platessa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Pleuronectes platessa naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Pleuronectes platessa 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 bilirubin + UDPglucuronate no activity Pleuronectes platessa bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.17 ? x * 52000-57000 Pleuronectes platessa
2.4.1.17 ? all values determined by SDS-PAGE Pleuronectes platessa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.17 37
-
-
 Pleuronectes platessa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.17 7
-
 1-naphthol as substrate Pleuronectes platessa