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Literature summary extracted from

  • Park, W.; Seto, H.; Hakenbeck, R.; Matsuhashi, M.
    Major peptidoglycan transglycosylase activity in Streptococcus pneumoniae that is not a penicillin-binding protein (1985), FEMS Microbiol. Lett., 27, 45-48.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.129 Triton X-100
-
 Escherichia coli
2.4.1.129 Triton X-100 up to 0.6% Streptococcus pneumoniae

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.129 Moenomycin
-
 Escherichia coli
2.4.1.129 Moenomycin
-
 Streptococcus pneumoniae
2.4.1.129 Triton X-100 up to 0.6% Streptococcus pneumoniae
2.4.1.129 Vancomycin
-
 Escherichia coli
2.4.1.129 Vancomycin
-
 Streptococcus pneumoniae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.129 membrane
-
 Escherichia coli 16020
-
2.4.1.129 membrane
-
 Streptococcus pneumoniae 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.129 Escherichia coli
-
-
-
2.4.1.129 Streptococcus pneumoniae
-
-
-
2.4.1.129 Streptococcus pneumoniae R6cwl
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.129 partial Streptococcus pneumoniae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.129 additional information the enzyme possesses peptidoglycan transglycosylase activity that lacks penicillin-binding activity Streptococcus pneumoniae ?
-
 ?
2.4.1.129 additional information the enzyme shows both transglycosylase and transpeptidase activities Escherichia coli ?
-
 ?
2.4.1.129 additional information the enzyme possesses peptidoglycan transglycosylase activity that lacks penicillin-binding activity Streptococcus pneumoniae R6cwl ?
-
 ?
2.4.1.129 [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
-
 Escherichia coli [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate
-
 ?
2.4.1.129 [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
-
 Streptococcus pneumoniae [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate
-
 ?
2.4.1.129 [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
-
 Streptococcus pneumoniae R6cwl [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate
-
 ?