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Literature summary extracted from
- The oligosaccharyltransferase complex from pig liver: cDNA cloning, expression and functional characterisation (2001), Glycoconj. J., 17, 767-779.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 2.4.99.18 | cloning of OST48, ribophorin I, ribophorin II and expression in COS-1 cells | Sus scrofa |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.4.99.18 | endoplasmic reticulum | OST48, ribophorin I and ribophorin II possess a type I membrane topology with the bulk of their polypeptide chains directed to towards the lumen of the endoplasmic reticulum | Sus scrofa | 5783 | - |
| 2.4.99.18 | membrane | OST48, ribophorin I and ribophorin II possess a type I membrane topolyogy with the bulk of their polypeptide chains directed towards the lumen of the endoplasmic reticulum | Sus scrofa | 16020 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 2.4.99.18 | 48900 | - |
x * 48900, OST48, + x * 68700, ribophorin I, + x * 69300, ribophorin II + ?, calculation from nucleotide sequence | Sus scrofa |
| 2.4.99.18 | 68700 | - |
x * 48900, OST48, + x * 68700, ribophorin I, + x * 69300, ribophorin II + ?, calculation from nucleotide sequence | Sus scrofa |
| 2.4.99.18 | 69300 | - |
x * 48900, OST48, + x * 68700, ribophorin I, + x * 69300, ribophorin II + ?, calculation from nucleotide sequence | Sus scrofa |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.4.99.18 | Sus scrofa | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.4.99.18 | liver | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.99.18 | dolichyl diphosphooligosaccharide + protein L-asparagine | - |
Sus scrofa | dolichyl diphosphate + glycoprotein with the oligosaccharide chain attached by N-glycosyl-linkage to protein L-asparagine | - |
? |  |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 2.4.99.18 | ? | x * 48900, OST48, + x * 68700, ribophorin I, + x * 69300, ribophorin II + ?, calculation from nucleotide sequence | Sus scrofa |
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